Data for the year 2021 are preliminary. Due to the impact of the COVID-19 pandemic, data for years 2020 and 2021 should be interpreted with caution. Visit for the latest Coronavirus Disease (COVID-19) updates.
COVID-19 disruptions in HIV, diagnosis, care and reporting of deaths during 2020 have also made incidence, prevalence, and knowledge of status estimates derived from a CD4-based model, unreliable. Therefore, the HIV surveillance supplemental report Estimated HIV Incidence and Prevalence in the U.S., which provides data on estimated incidence, prevalence, and knowledge of status in the U.S., was not published by CDC this year.

Overview | AHEAD

Data Methods

Learn more about the data that informs AHEAD.

Two people looking at each other, smiling


There are 6 core EHE indicators reported on this site. Five of the 6 core EHE indicators are from the National HIV Surveillance System (NHSS), managed by the Centers for Disease Control and Prevention (CDC). NHSS is the primary source for monitoring HIV trends in the United States. The CDC funds and assists state and local health departments to collect the data. States and local jurisdictions, including the District of Columbia and Puerto Rico, have laws or regulations that require confidential reporting by name for adults and adolescents (i.e., persons aged 13 and older) with a confirmed HIV diagnosis. After the removal of personally identifiable information, data from these reports are submitted to CDC. Health departments report these de-identified data to CDC so that information from around the country can be analyzed to determine who is being affected, which can inform where HIV prevention and treatment resources are most needed. The PrEP coverage indicator uses 4 different data sources. Please see PrEP coverage section for more details.

Data on HIV diagnoses should be interpreted with caution. Data may not be representative of all persons living with HIV because not all infected persons have been tested. Also, many states offer anonymous testing; the results of anonymous tests are not reported to the confidential name-based HIV registries of state and local health departments. The data presented on this site provide the minimum number of persons for whom HIV infection has been diagnosed and reported to NHSS. In addition, because surveillance practices differ, the reporting and updating of a person’s clinical and vital status differ among states. NHSS data are considered preliminary until a 12-month reporting lag has been reached.

The NHSS data displayed on this site may not be comparable to surveillance data published by individual jurisdictions. This is because: (1) CDC de-duplicates cases at the national level, and (2) national data have been statistically adjusted to account for missing transmission category. For more information, please refer to the CDC fact sheet at the following link:

The baseline year for HIV surveillance data used for calculating the Ending the HIV Epidemic (EHE) indicators (incidence, diagnoses, knowledge of status, linkage to care, viral suppression, and PrEP) is 2017. Data for the years 2020 and 2021 should be interpreted with caution due to the impact of the COVID-19 pandemic on HIV case surveillance activities in state/local jurisdictions and use of prevention services such as PrEP.

Definitions for each indicator can be found at the following pages: